DSG1 and pemphigus: Since understanding the long-term modifications of the DSG-specific autoimmune B cell response after rituximab treatment might improve the way we use this drug, we longitudinally analyzed the transcriptomic and phenotypic profiles of one-cell sorted autoreactive DSG-specific B cells from patients with a newly diagnosed pemphigus (during the active phase of disease) and after treatment with rituximab or a standard CS regimen, and compared these results with those observed from non-autoreactive B cells.