We observed that the mRNA of 11 genes (IL-2, IL-5, IL-9, IL-12p40, IL-13, IL-17F, IL-21, IL-27p28, IFNγ, TGF β2, and APRIL) was not detected at baseline neither in DSG-positive, nor in DSG negative B cells from pemphigus patients, whereas all housekeeping genes were detected. This evidence concerns the gene DSG1 and pemphigus.