SPP1 and invasive breast carcinoma: Although the levels of CD11c (ITGAX), OPN (SPP1), and PD-1 (PDCD1) in human invasive breast carcinomas were significantly higher than those in normal human mammary glands (Extended Data Fig. 2a), there was no significant difference in CD206 (MRC1) expression between these two types of tissue (Extended Data Fig. 2a).