BHLHE41 and preeclampsia: Women with early-onset preeclampsia and late-onset preeclampsia also had lower serum SHARP1 levels than non-preeclamptic women (3.3 ng/ml vs 4.7 ng/ml, p < 0.01 and 3.7 ng/ml vs 4.7 ng/ml, p < 0.01, respectively) (Table 3).