Expression of RHOU (Ras homolog family member U) was significantly increased, whereas TIMM9 (translocase of inner mitochondrial membrane 9) and ATP5A1 (ATP synthase F1 subunit alpha) were significantly decreased in C9-ALS myogenic progenitors (Fig. 4A), and NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11) was significantly decreased in C9-ALS myocytes (Fig. 4C). The gene discussed is RHOU; the disease is amyotrophic lateral sclerosis.