GPT and asthenia: Four patients (7%) discontinued due to treatment-related AEs: 1 due to grade 2 pyrexia; 1 due to grade 3 elevated ALT; 1 due to grade 1 creatinine increase, grade 1 potassium increase, grade 3 fatigue, and grade 2 myalgia; and 1 due to grade 2 asthenia.