BIRC5 and colorectal cancer: Through use of the colorectal cancer cell line Colo320 transfected with the 1092bp (-1102 to -11, +1ATG) survivin promoter-driven luciferase report system to screen ~200 strains of imperfect fungi, a drimane sesquiterpene lactone (named SF002-96-1, Fig. 1w) was isolated in the fermentations of an Aspergillus species [99].