In contrast, 3D185 was inactive against 20 additional tumor cell lines that exhibited low expression or activation of FGFR and CSF-1R (IC50 > 1 μM) (Fig. 2g, Additional file 1: Table S5), further demonstrating that 3D185 is a highly potent and selective FGFR1/2/3 and CSF-1R inhibitor. The gene discussed is FGFR1; the disease is neoplasm.