The concentration of 3D185 required to inhibit cellular FGFR signaling or CSF-1R signaling was consistent with the IC50 value for in vitro proliferation (Additional file 1: Table S4, Figs. 2a-f), indicating that 3D185 inhibits the proliferation of the above cancer cell lines via targeting FGFR or CSF-1R signaling. Here, CSF1R is linked to cancer.