The avirulent S2 strain of B. suis, L. monocytogenes and the E. coli standard strain were used to infect RAW264.7 macrophage cells transfected with MmPrdx6 overexpression plasmids, and the total counts of viable bacteria and Prdx6 expression levels were detected at 2, 14 and 26 h post-infection. This evidence concerns the gene PRDX6 and infection.