In line with these results, So Yong Kim et al. (2008) have demonstrated that, as a LOX inhibitor, NDGA scavenges intracellular ROS, inhibits the tumor necrosis factor α (TNF-α)-induced ROS accumulation, blocks the TNF-α-induced NF-κB activation, and inhibits LPS-induced TNF-α production and NF-κB activation in ovalbumin-induced asthma in mice [39]. This evidence concerns the gene NFKB1 and asthma.