One of the severe asthma subtypes is a severe non-allergic eosinophilic asthma (SNEA), which is characterized by severe clinical course, frequent exacerbations of the disease, resistance to treatment including high doses of systemic glucocorticoids, and poorer clinical outcome [5, 6] as well as a good response to biologicals such as treatment with anti-IL-5 antibodies. Here, IL5 is linked to asthma.