PARP1 and non-small cell lung carcinoma: Detailed signaling pathways of transcriptional regulation of MMP-2/− 9 and expression of key marker genes in EMT pathways were investigated in NSCLC A549 and H1299 cells after exposure with 12C ion in presence and absence of PARP-1 inhibition using iPARP (olaparib or DPQ) or siRNA.