Such obesity risk modified by the TAS2R38 genetic variation was also maintained in the adjusted models: The OR for the CT genotype was 1.33 (95% CI: 1.06–1.67) and for the TT genotype was 1.75 (95% CI: 1.31–2.36). Here, TAS2R38 is linked to obesity due to melanocortin 4 receptor deficiency.