Univariate analysis (Table 2 and Figure 3) revealed that disease-specific survival (DSS) was significantly associated with pre-Tx tumor status (p = 0.0484), pre-Tx lymph node metastasis (p = 0.0059), post-Tx tumor status (p = 0.0014), vascular invasion (p = 0.0123), tumor regression grade (p = 0.0037), and CHD4 expression (p = 0.0373). The gene discussed is CHD4; the disease is metastatic malignant neoplasm in the lymph nodes.