In a recent article concerning a series of 456 breast carcinomas, we identified an unexpected strong positive link between ANRIL and the p16-CDKN2A/p15-CDKN2B/p14-ARF locus and a complex pattern of interactions between ANRIL, PRC2/PRC1, and several suppressive/oncogenic miRNAs [15]. The gene discussed is CDKN2A; the disease is breast carcinoma.