Conversely, most tumors revealed a strong positive correlation between ANRIL and the p16-CDKN2A/p15-CDKN2B/p14-ARF gene cluster levels of expression, especially HNSCC, ovary, thyroid, cervix, colon, kidney, bladder, brain, and breast (p < 0.0000001) (Table 2). This evidence concerns the gene CDKN2B and head and neck squamous cell carcinoma.