MAPK1 and Parkinson disease: Researchers have previously demonstrated that ROT induces neurotoxicity by caspase activation and apoptotic cell death, accompanied by the activation of pro‐apoptotic MAPK signalling pathways like p38 and JNK.35, 36, 37, 38, 39 Our study not only corroborated these results but additionally revealed that the neuroprotective effects of mild hypothermia in a ROT‐based PD cell model are mediated by RBM3.