Interestingly, LMP1’s localization to internal Golgi apparatus and MVB compartments and its packaging into exosomes for secretion have been investigated.16 Exosomes harboring LMP1 isolated from EBV‐infected B cells could be internalized by adjacent B lymphocytes, enhance proliferation, and drive B cell differentiation.17 LMP1‐positive exosomes enhance the motility and potential invasive ability of surrounding NPC tumor cells.18 Thus, it is likely that the LMP1 packaged into EVs or exosomes involves in oncogenesis by its multiple functions. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.