Meckes et al found that through the intercellular transfer of LMP1, signaling molecules, and viral miRNAs, exosomes may manipulate the tumor microenvironment and accordingly influence the growth of neighboring cells.27 However, the present study is the first to reveal that the EVs from LMP1‐positive NPC cells not only enhanced proliferation and invasiveness while inhibiting apoptosis but also promoted radioresistance in recipient NPC cells. This evidence concerns the gene PDLIM7 and neoplasm.