Possibly, this relates to the ability of this antibody to block the binding of both activin A and myostatin to the ACVR2.27, 34, 50 Myostatin deficiency has previously been shown to be highly anabolic.51, 52 Whether myostatin also has a role in regulating IL‐6 secretion, and thereby is influencing cachexia development, cannot be excluded but is beyond the scope of this study. Here, MSTN is linked to Cachexia.