The aims of this study were to identify the association between CYP17 MSP AI (T-34C/rs743572) and CYP19 (Trp39Arg/rs2236722) polymorphisms with susceptibility to PCOS and also with lipid profile and sex hormone levels in a population from Western Iran with ethnic background of Kurds. The gene discussed is CYP17A1; the disease is polycystic ovary syndrome.