CCL2 and stroke disorder: As shown in Fig. 2, the expression of M1 (MCP-1, iNOS, CD32, CD86 and IFN-γ) and M2 (Ym1/2, Arg-1, CD206, BDNF and TGF-β) markers was significantly increased in vehicle-treated stroke mice 1, 3, 7, and 14 days after MCAO.