PLAUR and neoplasm: Although the sample size for the clinical tumor tissues is relatively small, it will be important to design clinical studies to assess the prognostic value of increasing uPAR expression in patients with OSCC based on the status of uPAR expression in primary tumors (Supplementary Fig. S8), since cetuximab-treated OSCC patients have traditionally been divided into two groups (i.e., those with and without cetuximab resistance).