The significance of normalization of the remaining 9 proteins by GC (CCDC80, CNDP1, ANGT, CRDL1, SHBG, IGFBP2, IGFBP3, IGFBP5, ApoL1) and further decrease in AGER, CNTN4 and OMD by GC remains unclear. The gene discussed is APOL1; the disease is occult macular dystrophy.