Furthermore, levels of the Pim-1 and CXCR4 proteins expression were detected in patients with AML carrying FLT3-ITD mutants and MV4-11 cells but not in the normal control group, patients with AML carrying FLT3-wt or HL-60 cells (Fig. 2B). The gene discussed is FLT3; the disease is acute myeloid leukemia.