The purpose of this study is to examine the expression of FLT3-ITD, STAT5/p-STAT5, Pim-1, and CXCR4 in experimental and control groups and to elucidate the importance of the CXCL12/CXCR4 axis to the pathogenesis of FLT3-ITD-mutated AML. Here, PIM1 is linked to acute myeloid leukemia.