To investigate whether survivin induced by ESW indeed contributes to anti-apoptotic effect on myocardium in the acute DOX-induced cardiomyopathy model, the expression levels of Bcl2, the anti-apoptotic protein, were compared among control, YM155, DOX, ESW + DOX, and YM155 + ESW + DOX groups. This evidence concerns the gene BIRC5 and cardiomyopathy.