CD8A and neoplasm: Consistent with the latter, in Nucl-TAP-treated mice, DC and NK cells infiltrated tumor lesion at early time points (Fig. 4b, c, day 9) that preceded the appearance of CD8+ T cells (Fig. 4b, c, day 12) and the tumor infiltrating NK cells exhibited a mature phenotype at day 9 and activated phenotype at day 12 (Supplementary Fig. 4c).