LRPAP1 and neoplasm: Marijt et al. 28 have shown that tumor cells in which TAP expression is knocked out by CRISPR/CAS9 present a new HLA-A2-restricted peptide derived from the housekeeping LRPAP1 protein that was capable of activating a T cell clone specific to the TAP deficiency-induced HLA-A2-restricted peptide.