Similarly, in a second model, CD8+ T cells isolated from 67NR breast carcinoma tumor-bearing mice treated with Nucl-TAP, but not Nucl-Ctrl, siRNAs inhibited the growth of 67NR tumor cells though to a lesser extent than 67NR tumor-bearing mice treated with Nucl-TAP siRNA (Fig. 4l). Here, CD8A is linked to neoplasm.