There were 20 out of 46 (43.5%) Gsdme KO and 25 out of 54 (46.3%) WT mice with one or more colon adenocarcinomas (Figure 4E,F), with a median of one adenocarcinoma/mouse (range: 1–6) for the Gsdme KO mice and a median of one adenocarcinoma/mouse (range: 1–7) for the WT mice (Figure 5 and Table S4). This evidence concerns the gene GSDME and colon adenocarcinoma.