NFE2L2 and asthma: Several studies have demonstrated that Keap1/Nrf2 signaling plays a pivotal role in the attenuation of both acute and chronic inflammation in several diseases (i.e., rheumatoid arthritis, asthma, emphysema, gastritis, and atherosclerosis) through its ability to normalize mitochondrial function, restore redox homeostasis, and suppress the production of inflammatory mediators [39,40,41,42,43,44].