IL4 and Alzheimer disease: Since Glyteer inhibits IL-4-induced upregulation of IL-31 RA expression and IL-4-induced Ccl 17 and Ccl 22 production in BMDCs, the dual effects of Glyteer on IL-31RA expression and Ccl 17 and Ccl 22 production contribute to its inhibition of Ccl 17 and Ccl 22 production in AD.