In fact, chimeras generated with CD5- B-1 cells showed no more B-1 derived IgM ASC in their MedLN than uninfected chimeras, consistent with their previously reported deficiency in entering the MedLN after infection (Figure 4E, left panel) (Waffarn et al., 2015; Choi and Baumgarth, 2008). Here, CD40LG is linked to infection.