In these models, neuronal cell death associated with mutations in PD‐linked genes (SNCA, LRRK2, DJ‐1, PARK2, PINK‐1) involves varying degrees of activation of intrinsic (Iaccarino et al., 2007; Yamada, Iwatsubo, Mizuno, & Mochizuki, 2004) and extrinsic (Ho, Rideout, Ribe, Troy, & Dauer, 2009) apoptosis, autophagic cell death (Venderova & Park, 2012), and parthanatos (Kam et al., 2018). Here, LRRK2 is linked to Parkinson disease.