Several other ‘DTC-specific’ genes in this panel (PDGFRB, STEAP1, SRC, WNT5A, PTCH1), although not necessarily prognostic in this study, could also serve as potential therapeutic targets, even if they have proven less effective targets for the treatment of primary breast tumors in otherwise unselected patient population [24, 25]. This evidence concerns the gene PTCH1 and breast neoplasm.