It has been described that miR-K3, a Kaposi’s sarcoma-associated herpesvirus (KSHV) miRNA, facilitates cell migration and invasion via activation of the CXCR2/AKT pathway by repressing GRK2 expression [121], pointing to a role of GRK2 in suppressing KSHV-associated tumor progression. Here, GRK2 is linked to neoplasm.