Paradoxically, while expression of B7-H1 on the surface of tumor cells impairs dormant cancer cell-killing potential of T-cells, expression of same surface receptors by natural killer (NK) cells (induced by CXCL10) can activate them to prompt a cytotoxic T lymphocyte (CTL) response resulting in destruction of otherwise CTL-killing resistant dormant tumor cells in vitro and in vivo [108]. Here, CD274 is linked to neoplasm.