In a very recent study, Luo et al. reported that sequences of T cell receptor (TCR) α and β/complementarity-determining region (CDR) 3 were found in influenza HA nucleoprotein (NP) and HCRT tetramer-positive CD4+ T-cells, and also retrieved in INF-γ-secreting CD4+ T-cells stimulated with Pandemrix [57]. This evidence concerns the gene CD4 and influenza.