Protein expression levels of cleaved caspase-3, p-rps6, p-eIF4E, p-ATM, p-DNA-PKcs, 53BP1, VEGF-A, and HIF-1α in CRC xenograft tumor cells following each treatment were quantified as shown in Supplementary Figure S5B. The gene discussed is PRKDC; the disease is colorectal carcinoma.