Since ACE2 enzyme was discovered [5,6], some researchers have explored the association of single nucleotide polymorphisms (SNPs) of the gene (localized on chromosome Xp22) with hypertension, with special attention to G8790A polymorphism (rs2285666) in intron 3, nevertheless this issue remains inconclusive and most of studies were conducted in China [23]. This evidence concerns the gene ACE2 and hypertensive disorder.