S100A11 can also stimulate the proliferation of human pancreatic cancer cells and promote the G1/S phase transition of pancreatic cancer cells, the growth and invasion of ovarian cancer cells, and the growth of lung cancer cells.10, 31, 32 However, S100A11 has not been reported in GBM, and the molecular mechanisms of S100A11 function in human GBM were unclear and required clarification. This evidence concerns the gene S100A11 and pancreatic neoplasm.