RIPK1 and cirrhosis of liver: Because CHB patients suffered from chronic inflammation, and this is areason for induction of liver cirrhosis and hepatocellular carcinoma (HCC), the mostimportant CHB complications, it may be hypothesized that the up-regulation ofIPS-1 and RIP1 expression is a crucialmechanism to induce or stimulate chronic inflammation, and consequently livercirrhosis and HCC.