TGFB1 and chronic myelogenous leukemia, BCR-ABL1 positive: Another study showed that chronic myeloblastic leukemia (CML) derived exosome(another extracellular vesicle with smaller size than microvesicles) can promoteboth survival and proliferation of CML cells through an autocrine mechanism by aligand-receptor interaction between TGF-β1, found in CML-derived exosomes, and theTGF- β1 receptor on CML cells.