Specifically, cytokines that were previously shown to correlate with the cytolytic index (C1QA, C1QB, C1QC, CXCL9, CXCL10, CXCL11 and CXCL13) [7], were upregulated in CYT-high colorectal tumors. The gene discussed is C1QC; the disease is colorectal neoplasm.