MeCP2 initiates silencing with selective methylation on H3K9, thus creating a high-affinity binding site for suppressor of variegation 39H1(SUV39H1) proteins [33].To investigate the interaction between MeCP2 and SUV39H1, coimmunoprecipitation(Co-IP) experiments was used to perform in glioma cells. This evidence concerns the gene MECP2 and glioma.