Some studies have investigated the effects of miRNAs on LINC00460 and its functions, revealing that LINC00460 promotes cell proliferation and migration by upregulating the expression of the miR-149-5p-targeted genes IL6 in nasopharyngeal carcinoma [25] and CUL4A in colorectal cancer [23], by targeting miR-342-3p/KDM2a in gastric cancer [28], by regulating miR-338-3p in epithelial ovarian cancer [27], by targeting miR-302c-5p/FOXA1 in human lung adenocarcinoma [18], by sponging miR-613 in papillary thyroid carcinoma [26], and by targeting miR-539/MMP-9 in meningioma [31]. The gene discussed is IL6; the disease is colorectal cancer.