LINC00460 and head and neck squamous cell carcinoma: Since a pulmonary metastasis model by tail vein injection of A549 cells was successfully established [47–49], and the similar biological characteristics between A549 cells and HNSCC cells were also demonstrated according to previous studies [50–54], we finally used A549 cells for animal pulmonary metastasis assay to verify the in vivo functions of LINC00460.