Located on chromosome 13q33.2 and transcribed as a 913-nt transcript, LINC00460 has been reported to play important roles in tumorigenesis and progression in various tumors and is significantly correlated with survival in the context of several cancer types, including lung cancer [16–19], esophageal cancer [20–22], colorectal cancer [23, 24], nasopharyngeal carcinoma [25], papillary thyroid carcinoma [26], ovarian cancer [27], gastric cancer [28, 29], renal carcinoma [30], meningioma [31], and bladder and urothelial carcinoma [32, 33]. This evidence concerns the gene LINC00460 and esophageal cancer.