GPT and coronary artery disorder: After adjustment for conventional CAD risk factors, including age, sex, BMI, smoking and drinking history, DBP, TG, TC, LDL-C, FBG, ALT and AST, increased ESM-1 levels showed a higher OR of CAD (OR = 1.688/100 pg ESM-1, 95% CI =1.226–2.323, P < 0.001).