PDZRN3 and hepatocellular carcinoma: RGMB‐AS1 promoted cell proliferation, migration and invasion capabilities of lung cancer and thyroid papillary cancer.35, 36 RGMB‐AS1 was down‐regulated as an independent favourable prognostic factor for hepatocellular carcinoma patients.37 The biological function of the remaining lncRNAs (TMEM161B‐AS1, CADM3‐AS1, LINC00293, LINC00910, LINC01187, PDZRN3‐AS1 and ZBED5‐AS1) in our signature has not been investigated in previous studies; thus, further studies are required to investigate the underlying molecular mechanisms of these diagnostic lncRNAs.