EGFR and rheumatoid arthritis: For RA SFs, the FcεRI signaling pathway, the ERBB signaling pathway, the calcium signaling pathway, the VEGF signaling pathway, the chemokine signaling pathway, and the cytokine-cytokine receptor interaction were enriched in state 5, while for OA SFs, only the FcεRI signaling pathway was enriched in state 5 (Figure 4(c)).