Our previous case-control study of a panel of candidate polymorphisms has shown a significant association of the following genotypes with increased CRC risk: DCC (32008376 G/G(A), MLH1 (-93G/G(A), TP53 (Pro72Pro), GSTT1 deletions, and GSTM1 deletions (57). This evidence concerns the gene TP53 and colorectal carcinoma.