A computerized, systematic search was performed on April 17, 2019, using combinations of the following search keywords: granulocyte colony-stimulating factor, female infertility, thin endometrium, recurrent implantation failure, granulocyte colony-stimulating factor and female infertility, granulocyte colony-stimulating factor and implantation failure, granulocyte colony-stimulating factor and follicular fluid, granulocyte colony-stimulating factor, and thin endometrium. The gene discussed is CSF3; the disease is female infertility.