SNCA and Parkinson disease: More recently, the annual killifish Nothobranchius furzeri, which (i) has a naturally short lifespan of 3 to 6 months, (ii) exhibits age-dependent degeneration of dopaminergic and noradrenergic neurons, and (iii) develops brain accumulation of inclusion bodies containing α-synuclein, has been proposed as a possible animal model to study mechanisms underlying PD which takes aging into account [24].