Future studies exploiting different laminopathic animal models, including murine LmnaH222P/H222P KI, Lmna∆K32 KI, or Lmna KO (respectively, reproducing conditions very close to human cardiomyopathy, L-CMD and EDMD [101, 120, 121]), would enable further novel insights into the role of Ankrd2 in the pathophysiology of muscular laminopathies. Here, LMNA is linked to Emery-Dreifuss muscular dystrophy.