Mutations in LMNA gene cause a variety of muscular diseases including EDMD, limb-girdle muscular dystrophy 1B (LGMD1B), dilated cardiomyopathy with conduction defects (DCM1A), and LMNA-related congenital muscular dystrophy (L-CMD) [60, 81, 82]. The gene discussed is LMNA; the disease is Emery-Dreifuss muscular dystrophy.