Cluster 2, associated with anterior caudate, is enriched in genes involved in vasodilation and catecholamine secretion from the adrenal gland cluster 3, expressed in the inferior temporal lobe, and contained three genes (PCSK1, CARTPT, and JAK2) associated with leptin and CCK8 activation in inferior (nodose) ganglia neuron; the members of this cluster are related to genes expressed in neuroendocrine cells, neuropeptides, and diseases of clonal eosinophilia (Seidah et al., 1991; Douglass and Daoud, 1996; Lacronique et al., 1997; Reiter et al., 2005; Reiter and Gotlib, 2017). Here, JAK2 is linked to Increased total eosinophil count.