TP53I3, which encodes a putative quinone oxidoreductase, mediates p53-mediated cell death; it is differentially expressed in ganglioglioma and is also associated with several types of brain tumors (Fassunke et al., 2008; Alajez et al., 2009; Ghassemifar and Mendrysa, 2012; Schulten et al., 2017). Here, TP53I3 is linked to brain neoplasm.