CELF1 and myotonic dystrophy type 1: It seems particularly interesting considering that aberrant alternative splicing is one of the most prominent molecular markers of DM1 (Philips et al., 1998; Wang et al., 2007) and it is linked with hyperphosphorylation of CUGBP1 protein (Kuyumcu-Martinez et al., 2007; Wang et al., 2009).